
ZO Skin Health®
A leave-on AHA lotion that combines glycolic and lactic acids to accelerate surface cell turnover. With consistent use it smooths rough texture, evens tone and boosts the effectiveness of anti-aging treatments, while soothing botanicals limit irritation.
Targets
The brand behind the product
ZO Skin Health® is a medical-grade skincare line founded in 2007 by dermatologist Dr. Zein Obagi and headquartered in Irvine, California. It is sold through aesthetic providers rather than at retail, so a regimen is selected and managed by a clinician.
ZO's founding premise is that healthy skin is functional, not cosmetic. After decades in dermatology practice, Dr. Obagi observed that most skincare addressed visible symptoms while leaving the underlying behavior of the skin unchanged. The line is built instead around skin health as a system: balanced renewal, barrier strength and resilience, sustained across every stage of life.
Rather than a shelf of standalone formulas, ZO organizes its range into five steps: Getting Skin Ready® to prepare the skin, then Correct, Strengthen, Protect and Optimize. A provider selects and sequences those steps into a protocol built around one person's skin. Preparation is non-negotiable in that sequence, since the skin has to be primed before the corrective steps can do their work.
Dr. Obagi spent decades as a practicing dermatologist before founding ZO Skin Health® in 2007, turning that clinical experience into structured protocols. The brand has grown through curated partnerships with providers rather than through retail distribution, and now operates globally from its Irvine, California headquarters.
Where much of the professional skincare market competes on individual hero formulas, ZO competes on architecture: how the products work together in a disciplined protocol. That places the provider at the center, designing and managing a system rather than recommending products, and it measures success by how the skin is functioning overall rather than by any single formula.
Getting Skin Ready® is the methodology ZO is best known for, a preparation step of cleansing, exfoliating and toning that opens every protocol. Across its formulas the line also carries proprietary complexes of its own, among them ZOX12®, alongside the in-office ZO 3-Step Peel.
Glycolic acid · lactic acid · calming botanical complex

ZO Skin Health®
PMA lightweight body lotion that pairs gentle exfoliating acids with retinol to smooth rough, bumpy texture and improve tone on arms, legs and torso. It hydrates while gradually firming and evening body skin, extending facial-quality results below the jawline.
Available online & in office
Buy online
ZO Skin Health®
AM · PMA daily eye cream that targets dark circles, puffiness and fine lines around the delicate eye area. Optical diffusers instantly brighten shadowed skin while treatment ingredients gradually firm, smooth and reduce visible signs of fatigue and aging.
Available online & in office
Buy online
ZO Skin Health®
AM · PMAn eye serum powered by clinically supported growth factor technology to improve expression lines, creasing and hollowness around the eyes. It plumps, hydrates and encourages healthier-looking skin for a visibly revived, more rested appearance.
Available online & in office
Buy online
ZO Skin Health®
PMA targeted retinol eye treatment for more advanced signs of aging around the eyes. It visibly reduces crow's feet and creasing, improves texture and firmness, and uses optical diffusers to soften the look of dark circles and puffiness.
Available online & in office
Buy onlineIn-office treatments our providers often pair with this product.
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Product information is provided for general educational purposes and is not medical advice. Individual results vary. Please consult your provider about what’s right for your skin.
Book a consultation and our providers will help you decide what's right for your skin and goals.